The Science

Over the past two decades, VOC sponsored researchers have:

  • Identified the gene mutation responsible for ocular albinism type 1 (OA1), an X-linked recessive disorder in which the retinal pigment epithelium lacks pigment, while the hair and skin appear normal.
  • Developed the first genetic test for OA, allowing for prenatal diagnosis and carrier screening. 
  • Created an OA1 mouse model with many characteristics similar to those in human OA1.
  • Determined the biochemical features of the OA1 protein and its involvement in melanogenesis (the production of melanin, which gives color to skin, hair and the iris).
  • Studied the use of stem cells to regenerate damaged eye tissue in mice.
  • Demonstrated the efficacy of gene therapy for inherited eye diseases.
 

10+

Million Dollars Raised

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12+

Years Serving communities

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15+

Thousand children Impacted

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