Over the past two decades, VOC sponsored researchers have:
- Identified the gene mutation responsible for ocular albinism type 1 (OA1), an X-linked recessive disorder in which the retinal pigment epithelium lacks pigment, while the hair and skin appear normal.
- Developed the first genetic test for OA, allowing for prenatal diagnosis and carrier screening.
- Created an OA1 mouse model with many characteristics similar to those in human OA1.
- Determined the biochemical features of the OA1 protein and its involvement in melanogenesis (the production of melanin, which gives color to skin, hair and the iris).
- Studied the use of stem cells to regenerate damaged eye tissue in mice.
- Demonstrated the efficacy of gene therapy for inherited eye diseases.
Million Children have vision impairments
According to the World Health Organization, an estimated 19 million children face vision impairments.
Years funding research
The Vision of Children Foundation is proud to say that we have funded research for over 27 years now. 27 years worth of dedication to find a cure for genetic vision disorders.
Percent of cases of childhood blindness are caused by genetic factors
Genes play a highly significant role in eye diseases, some of which are highly prevalent in children and adults.